Scott lab @ The University of Melbourne
The Scott lab focuses on understanding microbial glycosylation systems as well as the link between glycosylation and virulence. Through the addition of carbohydrates to proteins, a process known as protein glycosylation, microbes are able to radically alter the function of proteins. Within a range of infections such as Malaria, Gonorrhoea and Salmonella, microbial protein glycosylation is used for both defensive and offensive processes; enabling pathogens to fortify themselves against the host immune response or to disarm the host’s ability to resist infection. By better understanding these systems the Scott lab aims to provide new insight into the mechanisms of pathogenesis of life-threatening infections such as those caused by Burkholderia species. To achieve this, our work focuses on developing and applying new methodologies to monitor glycosylated and non-glycosylated proteins using proteomics and mass spectrometry.
Interested in our work, get in touch
We love working on microbial Glycosylation and Proteomics related problems, if you are interested in what we do or have an interesting biological problem you want our help with drop us an email. The Scott lab is always on the lookout for new team members and collaborators.